• br A total of studies reported absolute concordance in KRAS

  2020-08-09

  

  A total of 9 studies reported absolute concordance in KRAS point mutations within codons 12 and 13, despite apparent differences in se-quencing methodologies, suggesting the stability in KRAS status be-tween the primary and metastatic sites [53,54,59,63,66,81,88,91,92]. Table 3 Of note, Tórt

• br Introduction br Metastatic breast cancer also

  2020-08-07

  

  1. Introduction Metastatic breast cancer, also known as metastases, is a stage of breast cancer where tumor cells have diffused to distant sites by virtue of blood and lymphatic circulation [1,2]. Distant metastases account for 90% of breast cancer-related deaths [3]. Despite the rapid advances

• br Conclusions br This study expands on

  2020-08-07

  

  3. Conclusions This study expands on the discovery of the high efficacy in vitro in a human clear-cell renal carcinoma cell line displayed by bime-tallic titanocene-gold derivatives. One of the compounds (Tita-nocref) had been described as extremely efficacious in vitro and Fig. 7. Heat map

• him br him Patient s wife expressed motivation to

  2020-08-07

  

  him.” him.” “Patient's wife expressed motivation to adhere to recommendations and stated that going through this process with her husband has changed the way she looks at her own health.” Seeing benefits “Exercise helped improve symptoms of leg cramps throughout the night.” “Caregiver

• br A database containing pattern cells selected by a

  2020-08-07

  

  A database containing 1577 pattern Temozolomide selected by a medical expert was used in the experiments. The cell pattern data were acquired from 39 fields of view, obtained from nine patients with detected breast cancer. Fig. 5. Exemplary fields of view of analyzed images: left column – vari

• br Results from our study

  2020-08-06

  

  Results from our study support previous reports that tooth loss was significantly associated with increased lung cancer risk. In the Health Professionals Follow-Up Study, among European American male po-pulations with high educational attainment, having fewer teeth was associated with an increased

• br Introduction br Colorectal cancer CRC is

  2020-08-06

  

  Introduction Colorectal cancer (CRC) is the third leading cause of cancer-related death worldwide [1]. Since the adoption of anti-EGFR and anti- Abbreviations: 5-Aza-CdR, 5-Aza-2′-deoxycytidine; CCLE, the Cancer Cell Line Encyclo-pedia; CIMP, CpG island methylator phenotype; EGFR, epidermal

• br Kent R Intelligibility in speech disorders

  2020-08-05

  

  [7] Kent R. Intelligibility in speech disorders. Amsterdam/Philadelphia: John Ben-jamins; 1992. [8] Yorkston KM, Beukelman DR, Tice TR. Sentence intelligibility test. Lincoln, NE: Tice technology services; 1996. [9] Auzou P. Les objectifs du bilan de la dysarthrie. In: Auzou P, Rolland Mon-

• br Fig Identification of PC luc

  2020-08-02

  

  Fig. 4. Identification of PC-3-luc cell apoptosis induced by recombinant adenovirus using Hoechst and Annexin V staining. (A) Morphological changes under fluorescence microscopy after Hoechst staining. PC-3-luc SCH 58261 were treated with Ad-VT, Ad-T, Ad-vp3, and Ad-mock for 24, 48, and 72 hou

• br Herein we reported novel NPs

  2020-08-02

  

  Herein, we reported novel NPs based on PEO-PBO-loaded LA-SN38 (EBNPs). The EBNPs with small size and narrow distribution, and could effectively control the release rate of SN38. Through in vitro cytotoxi-city and apoptosis assay, we demonstrated EBNPs were more effective in antitumor of human colo

• br In the present study we examined the expression

  2020-07-29

  

  In the present study, we examined the expression of eight ANGPTLs in six human gastric cancer cell lines (two AFPGCs and four common types of gastric cancer cell lines). We explored how the proliferation, migration, invasion and tube formation ability changed in HUVECs treated with recombinant pro

• br Conclusions Only a quarter

  2020-07-29

  

  Conclusions: Only a quarter of our respondents utilize FT in their practice with surgeon’s experience being the important independent predictor for using FT. Majority of respondents though consider FT to be beneficial in CaP management, would use it more often if provided more reliable and cost-ef

• br Table br Antiproliferative activity of

  2020-07-26

  

  Table 1 Antiproliferative activity of compounds 9–22 against human cancer cell lines. Compounds Cell viability Prostate Colorectal Liver a SD: standard deviation, all experiments were independently performed at least three times. more potent than the standard (2) against Hep3B ce

• br Corresponding author at Moo Amphoe

  2020-07-06

  

  Corresponding author at: 99 Moo 9, Amphoe Muang, Phitsanulok 65000, Thailand. E-mail address: [email protected] (W. Tiyaboonchai). Herbal drugs or traditional medicine have been used for a long time in Asia with impressive therapeutic activities. Recently, α-mangostin, obtained from the pericarp

• CAY10683 br Reverse transcription polymerase chain reaction

  2020-03-24

  

  2.2. Reverse transcription-polymerase chain reaction (RT-PCR) Total RNA was extracted from 1 × 105 cells using TRIzol reagent according to the manufacturer's instructions (Gibco). Total RNA (2 μg) was reverse-transcribed with MMLV reverse transcriptase (Bioneer, Daejeon, Korea) for 1 h at 42 °C

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