• br INTRODUCTION br Pancreatic cancer is a major threat

  2021-03-03

  

  INTRODUCTION Pancreatic cancer is a major threat to human health with very few effective therapies and prognoses.1–3 As the fourth primary death cause of all different cancers, the survival rate of pancreatic cancer is incredibly low.4 Despite improvements made to pancreatic cancer therapies, t

• br Introduction br Selenium is well renowned as

  2021-03-03

  

  1. Introduction Selenium is well-renowned as an operational N-octanoyl-L-Homoserine lactone in the solar cells, semi-conductor devices, and photographic exposure meters. Its uniqueness lies in the special physical properties such as high aniso-tropy of thermal conductivity, optical conductivity

• br Materials and methods br obtained from

  2020-08-30

  

  2. Materials and methods obtained from the American Type Culture Collection (ATCC). The TGF-β-sensitive Mv1Lu cell line was donated by Dr. H. López Muñoz at the UIDCC, FES-Z, UNAM, México. To analyze the participation of the adenosinergic pathway in the secretion and expression of TGF-β in C

• br Table br Association of CD expression

  2020-08-30

  

  Table 2 Association of CD155 expression with clinicopathological characteristics in BC patients. Characteristics CD155 Expression Pearson x2 P-value Low or no High Total Postmenopausal 0.125 Ductal Negative Negative 119 Negative 96 skin) Lymph node I N

• br Cell migration assay was performed based on the

  2020-08-30

  

  Cell migration assay was performed based on the modified Boyden chamber assay method using Trevigen's Cultrex® cell migration 24-well assay kit according to manufacturer's protocol, and a detailed description of the procedure is provided in the Supplementary Materials and Methods section. Cell

• br ated inhibition of TUBB mRNA expression

  2020-08-28

  

  ated inhibition of TUBB3 mRNA expression in HT-29 1132935-63-7 (Figure 5D). Cathelicidin Inhibited Colon Cancer Metastasis via P2RX7 To validate this receptor pathway in vivo, we in-jected KN62 into the HT-29-loaded nude mice. Injection of KN62 did not significantly affect colon cancer metas

• br The feature matrix F was obtained by multiplying a

  2020-08-28

  

  The feature matrix F was obtained by multiplying a transposed  matrix AScore with matrix W , with size N × K , where each K columns represents the coefficient for each subject. To determine the association level of each factor with each cancer type, elastic net regression models were fitted

• br Conclusions Breastfeeding for as

  2020-08-24

  

  Conclusions. Breastfeeding for as few as 3 months is associated with reduced EOC risk. Although this associa-tion decreases over time, it persists for more than 30 years. Longer cumulative duration, increasing number of breastfeeding episodes, and earlier age at first breastfeeding episode are eac

• br proposed a transfer learning method Based

  2020-08-18

  

  [21] proposed a transfer learning method. Based on the pretraining model of GoogLeNet and ResNet, they first classified each patch of one image and then used the majority voting method to obtain image-wise classification results. Vang et al. [22] first proposed using Google In-ception-V3 to perfor

• br There are some limitations in this study This study

  2020-08-18

  

  There are some limitations in this study. This study considers samples from multiple clinical locations which, although critically im-portant, is underused in metabolomics study design. However, knowl-edge of sample demographics is a limitation. Although statistically important clinical features s

• br Cell Reports Resource br Breast Cancer Classification Bas

  2020-08-18

  

  Cell Reports Resource Breast Cancer Classification Based on Proteotypes Obtained by SWATH Mass Spectrometry Pavel Bouchal,1,2,10,* Olga T. Schubert,3,4 Jakub Faktor,2 Lenka Capkova,1 Hana Imrichova,1,5 Karolina Zoufalova,1 Vendula Paralova,1 Roman Hrstka,2 Yansheng Liu,6 Holger Alexander Eb

• br Results br Bou reduces the viability of rectal cancer

  2020-08-18

  

  3. Results 3.1. Bou reduces the viability of rectal cancer cells without apoptosis HCT-116 cells treated with Bou dose dependently decreased cell viability, with an IC50 value of 12.1 μM after 24 h of incubation (Fig. 1A). In comparison, there was no detectable effect of Bou on the cell vi

• Trimbos JB Vergote I Bolis G Vermorken JB Mangioni C

  2020-08-18

  

  [52] Trimbos JB, Vergote I, Bolis G, Vermorken JB, Mangioni C, Madronal C, Franchi M, Tateo S, Zanetta G, and Scarfone G, et al (2003). Impact of adjuvant chemotherapy and surgical staging in early-stage ovarian carcinoma: European Organisation for Research and Treatment of Cancer-Adjuvant ChemoTher

• br wrap them Videos S S S and S

  2020-08-18

  

  wrap them (Videos S4, S5, S6, and S7, SI). Both MIA 1802088-50-1 and PSCs in co-culture actively migrated on CS-HA coated plates, especially when the ratio of PSCs increased (Fig. S6, SI). The moving patterns (trajec-tories) of MIA cells alone and PSCs alone are shown in Fig. 3B. The moving patte

• br Quantification of NETs br NETs sca

  2020-08-18

  

  2.5. Quantification of NETs NETs scaffolds in coculture were digested with 250 mU/mL of mi-crococcal nuclease (LS004797, Worthington Biochemical Corp.) and then stained with 2.5 μM Sytox Orange (S34861, Molecular Probes) for 10 min at room temperature. Quantification was measured using a fluorom

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