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Gastrin I br Figure Changes in Programmed Death ligand PD
2022-05-09
Figure 1 Changes in Programmed Death-ligand 1 (PD-L1) Expression From Initial Stage to Recurrence in Nonesmall cell Lung Cancer. Four Immunohistochemistry Score Groups Were Defined: TC0 le ([TC0) (A) and Biopsy ([TC3) (B) after Adjuvant Therapy. Increase in PD-L1 Expression From Initial Tumor Samp
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Cancer Letters br sTRAIL and mbTRAIL expression
2022-05-09
Cancer Letters 440–441 (2019) 202–210 sTRAIL and mbTRAIL expression in 5K-ASCs and 40K-ASCs after 5 days of culture. The mean fluorescence intensity of mbTRAIL increased by approximately 5-fold in 40K-ASCs on day 5 compared to that in 5K-ASCs on day 1. The mean fluorescence intensity of DR5 sl
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6-diazo-5-oxo-L-nor-Leucine Corresponding author at Department of Biochemistry School
2022-05-09
Corresponding author at: Department of Biochemistry, School of Medicine, University of Buenos Aires, Paraguay 2155 5th floor, CABA C1121ABG, Argentina. E-mail address: [email protected] (E.J. Podesta). 1 These authors have contributed equally to this work. by human arterial smooth muscle c
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br Materials and methods br A panel of
2022-05-09
2. Materials and methods A panel of hematologic malignant (Nalm-6, REH, RPMI8226, KMM-1, K562, U937, KG-1, and NB4) and solid tumor (U87, SKBR3, and T4D7) cells were grown in RPMI 1640 medium supplemented with 2 mM L-glutamine, 10% heat inactivated fetal bovine serum, 100 U/ml and 100 µg/ml str
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Dihexa br Objective To explore differences
2022-05-07
Objective: To explore differences in psychosocial factors between HPV+ OPSCC patients versus OCSCC smokers. Methods: A prospective cohort study at a single multidisciplinary, tertiary care HNC center was completed with recruitment from 2010 to 2013 using self-administered questionnaires before tre
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The model with the best precision F
2022-05-06
The model with the best precision, F1-score, and accuracy did not use machine learning, but rather leveraged list structures. With respect to the manual gold standard the list model achieved 90.14 precision, 60.69 recall, 75.41 F1-score, and 92.60 accuracy. The list model also provided optimal perfo
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br Conflicto de intereses br Los autores
2022-05-06
Conflicto de intereses Los autores declaran no tener ningún conflicto de intereses. Referencias 2. Ramos Munos˜ WC, Venegas Ojeda DR. Análisis de la Situación del Cáncer en el Perú 2013 Lima: Dirección General de Epidemiología, Ministerio de Salud. [Inter-net]. 2013 [consultado 10 Ago 201
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Latrunculin A br References br Lim K Small W Jr
2022-05-06
References 1. Lim K, Small W Jr., Portelance L, et al. Consensus guidelines for delineation of clinical target volume for intensity-modulated pelvic radiotherapy for the definitive treatment of cervix cancer. Int J Radiat Oncol Biol Phys 2011;79:348-355. 2. Bondar ML, Hoogeman MS, Mens JW, e
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br To investigate the potential toxic e ects of
2022-05-04
To investigate the potential toxic effects of both miRNAs and delivery agents, an in vitro approach revealed that miR-660 replacement did not induce any changes in both mouse and human normal cells. Interestingly, lipid-nanoparticle delivery of synthetic miR-660 had no immunological off-target or ac
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br Statistical analysis br All statistical analyses
2022-05-04
2.11. Statistical analysis All statistical analyses were performed using SPSS software (version 18.0, SPSS Inc., Chicago, IL). Student’s t-test for unpaired data was used to evaluate statistical differences between mean val-ues. All data are presented as the mean ± standard deviation (SD), and
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br The total RNA was extracted from cells using
2022-05-04
The total RNA was extracted from cells, using TRIzol (Takara, Japan). RNA concentration was measured by NanoDrop 2000 spectrometer. 500 ng of total RNA from each sample was reversely transcribed to cDNA using Prime Script RT Master Mix (Takara, Japan). RT-PCR was performed in the following conditi
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br The age groups of the seven
2022-04-29
The age groups of the seven clinicians were: ≤39 years (5) and ≥40 years (2). Three were females and four males. Their clinical ex-periences in breast cancer and palliative care ranged from 3 to 15 years. Table 1 Themes and sub-themes. Three were certified palliative care specialist (1 nu
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br Conclusions Complete resection without positive surgical margins is
2022-04-29
Conclusions: Complete resection without positive surgical margins is essential for the treatment of the patients with T1 and T2 ear cancers. Prophylactic superficial parotidectomy or neck dissection is not mandatory for T1 and T2 diseases, as long as precisely extent of disease is assessed preoper
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br The expression of molecules
2022-04-28
The expression of molecules related to epithelial-mesenchymal transition (EMT) was examined in the MIA PaCa-2-A and MIA PaCa-2-R CAY10683 by DNA microarray (Supplement Table 2). CDH1, an epithelial marker, was expressed in the MIA PaCa-2-A cells, but not in the MIA PaCa-2-R cells. However, the ex
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br Dys regulated cell cycle progression is an
2022-04-28
Dys-regulated cell cycle progression is an important mechanism of Okadaic acid cancer development (15). CDKN1A-interacting zinc finger protein 1 (CIZ1) is primarily identified as regulator of G1/S cell cycle (16-18). It functions as a nuclear protein that directly regulates the intracellular local